Introduction of Carboxyl Magnetic Beads for Nucleic Acid Extraction
Carboxyl-modified superparamagnetic microspheres have the characteristics of superparamagnetism, fast magnetic responsiveness, rich carboxyl functional groups, relatively high specific surface area, monodispersity and submicron particle size, good long-term stability, and good inter-batch repeatability. , Can covalently couple peptides, proteins, nucleotides and other biological ligands to the surface of microspheres under the action of special chemical reagents (such as EDC). It is an important carrier tool in medical and molecular biology research. Using the optimized blocking agent can achieve a better effect of reducing the background value.
Characteristics of Carboxyl Magnetic Beads for Nucleic Acid Extraction
- Covalent bonding, low non-specific binding of nucleic acids
- Nucleic acid extraction carboxyl magnetic beads can bind the target substance in a short time
- The magnetic response time is short and the magnetic induction distance is large. The enrichment and transfer of magnetic beads can be easily realized with ordinary magnets, which avoids the harm of high magnetic field to the human body. At the same time, the magnetic beads are not easy to be sucked into the body by mistake, avoiding potential harm to the human body.